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4.3 Effect on neuro-developmental Throughout the developmental process, the brain exhibits heightened energy demands for synthesizing fundamental cellular structures, neurotransmitters, nucleic acids, proteins, carbohydrates, and lipids that are indispensable for neuronal growth and myelination (46, 47)

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BACE1) and -secretase cleave APP to produce A peptides, and A peptides exert neurotoxicity through various proposed mechanisms 28,29,30,31

The patience required during dose escalation is actually one of the most valuable aspects of the protocol